Dismiss Modal

Treatment

Understanding Septal Myectomy

Choose a preferred language

Septal myectomy is a type of open-heart surgery. It’s done to treat hypertrophic cardiomyopathy (HCM). This is when part of the heart muscle becomes thick. The septum of the heart can thicken because of a family history of the disease or from uncontrolled high blood pressure. And thyroid conditions may cause HCM. An infant can be at risk for HCM when the pregnant mother has diabetes. The surgery helps ease symptoms of the condition.

Four-chamber view of heart showing thickened septum toward left ventricle. Shaded area shows part of septum to be removed in septal myectomy.


What is hypertrophic cardiomyopathy?

The heart has four chambers. The two lower chambers are called ventricles. The left and right ventricles are separated by a wall of muscle called the septum. With hypertrophic cardiomyopathy, the walls of the septum and the ventricles may get thick. The septum may bulge into the left ventricle. This can partly block the blood flow out to the body. This causes the heart to work harder. It also causes symptoms such as tiredness, chest pains, dizziness, and feeling short of breath with regular activity. In extreme cases, the decreased blood flow from the heart chamber to the body can cause you to faint or to develop dangerous and life-threatening heart rhythms.


Why septal myectomy is done

In many cases, medicine can relieve the symptoms. But if medicine doesn’t work well to relieve symptoms, a septal myectomy often works. A woman with hypertrophic cardiomyopathy may need the surgery before becoming pregnant. This may be the case even if her symptoms aren’t severe.


How septal myectomy is done

During septal myectomy, a surgeon removes extra muscle from the thickened septum. This lets the blood empty from the ventricle more easily.


Risks of septal myectomy

All procedures have risks. The risks of septal myectomy include:

  • Irregular heart rhythms, such as heart block (see below).

  • Infection.

  • Bleeding.

  • Blood clots that can lead to stroke or heart attack.

  • Problems from anesthesia.

  • Aortic valve problems because of movement of the valve in surgery.

  • Removal of too much heart muscle.

  • Blood flow problems during surgery that can lead to poor pumping of the heart in the future.

Your own risks may vary based on your age and your overall health. Ask your health care provider which risks apply most to you. You may have a higher risk of problems if you have any of the following:

  • Chronic illness

  • Other heart conditions

  • Lung problems

  • Advanced age

  • Obesity

  • History of smoking

  • Infections

  • Diabetes


Heart block after septal myectomy

Heart block is a common problem after this surgery. Heart block is a disruption to the electrical signals through the heart. This can cause your heart to skip beats. Or it may beat too slowly. Some kinds of heart block need treatment with a pacemaker.

© 2000-2025 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.

Make an Appointment

Make an Appointment

Find a Doctor

Find a Doctor

Find a Location

Find a Location

Related Services

Heart & Vascular Center

Related Articles
Read article
Heart Health
Having Pericardiectomy

Pericardiectomy is a surgery to remove part or all of the sac around the heart. This lets the heart move more freely.

Read article
Heart Health
Having Carotid Angioplasty and Stenting

Angioplasty and stenting is a type of procedure to improve the blood flow in an artery or vein.

Read article
Heart Health
Biventricular Assist Device Implantation

A biventricular assist device (BiVAD) is an implantable pump designed to help your heart function better when both sides of your heart are failing.

Read article
Heart Health
First Aid: Heart Attacks

A heart attack is an emergency, but the condition that causes it usually takes years to develop. Over time, fatty substances collect on the walls of the heart's arteries. As these arteries become narrower, it's more likely that one will become fully clogged, causing a heart attack.