Symptoms

Non-Hodgkin Lymphoma: Symptoms


What are the symptoms of non-Hodgkin lymphoma?

Non-Hodgkin lymphoma is a type of cancer that starts in your lymphatic (lymph) system. The lymph system is part of your immune system.

Non-Hodgkin lymphoma may not cause symptoms right away. Slow-growing lymphoma, also called indolent lymphoma, may not cause symptoms until it grows very large. Aggressive lymphoma grows and spreads quickly. It can cause bad symptoms.

When lymphoma does cause symptoms, they can often seem like other health problems at first. That's because non-Hodgkin lymphoma can cause many different kinds of symptoms. It depends on where it starts in your body and the kind of lymphoma it is.

Here are some common symptoms of non-Hodgkin lymphoma:

  • Swollen, often painless, lymph nodes in the neck, groin, underarm, or above the collarbone

  • Fever without an infection

  • Chills

  • Feeling very tired

  • Swelling in the belly (abdomen)

  • Feeling full after eating only a small amount

  • Upset stomach (nausea), vomiting, or stomach pain

  • Coughing, shortness of breath, or trouble breathing

  • Chest pain or pressure

  • Swelling in your head and arms (called superior vena cava syndrome)

  • Headaches

  • Trouble thinking or moving parts of your body

  • Itchy, red or purple lumps under the skin

  • Infections that come back

  • Abnormal sweating, especially at night

  • Losing weight without trying

  • Easy bleeding or bruising


When to contact your doctor

Many of these symptoms are more often caused by other health problems. Still, it’s important to see a health care provider if you have these symptoms. Only a provider can tell if you have cancer.

Featured in

Online Medical Reviewer: Jessica Gotwals RN BSN MPH

Online Medical Reviewer: Susan K. Dempsey-Walls RN

Online Medical Reviewer: Todd Gersten MD

Date Last Reviewed: 03/01/2025

© 2026 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare provider's instructions.

Make an Appointment

Make an Appointment

Find a Doctor

Find a Doctor

Find a Location

Find a Location
Related Articles
Read article
Hematology
Chronic Myeloid Leukemia (CML): Surgery

In rare cases, CML may be treated with surgery to remove a swollen spleen. This is called a splenectomy. Here's what you need to know.

Read article
Immune Conditions
Acute Lymphocytic Leukemia (ALL): Diagnosis

If your doctor thinks you might have ALL, you will need certain exams and tests to confirm your diagnosis.

Read article
Hematology
Acute Myeloid Leukemia (AML): Stem Cell Transplant

Stem cells are immature cells that live in your bone marrow. They're the starter cells for all types of blood cells. A stem cell transplant uses stem cells to replace bone marrow that contains cancer.

Read article
Hematology
Chronic Myeloid Leukemia (CML): Tests After Diagnosis

After a diagnosis of CML, you'll likely need other tests. These tests help your doctor learn more about the cancer and how to treat it.